To evaluate the quality and significance of the projects’ scientific achievements and clinical contributions, the California Office of Planning and Research facilitated assessments of funded projects by expert scientists recruited from outside the state. This report serves as a summary of their assessments. According to the report, in its first three years the California Initiative to Advance Precision Medicine has awarded over $11 million, funding 11 projects across the state of which eight have been completed. Recently, Governor Gavin Newsom sought nominations for members of the new Precision Medicine Advisory Council to provide additional guidance to the Governor’s Office of Planning and Research on CIAPM related issues.